Process Development Engineer

PROCESS DEVELOPMENT ENGINEER

ABOUT THE ROLE

We are seeking a Process Development Engineer to support biopharmaceutical process development, digitalisation and Process Analytical Technology initiatives.

The role involves developing scale-down models, digital workflows and advanced monitoring solutions for upstream and downstream bioprocess operations. You will work within multidisciplinary teams to deliver commercial research and internal innovation projects.

KEY RESPONSIBILITIES

• Plan and deliver biopharmaceutical process-development programmes.
• Design scale-down models for manufacturing unit operations.
• Develop digital workflows for process monitoring and data acquisition.
• Apply chemometrics and multivariate data analysis to process data.
• Lead the development and implementation of PAT technologies.
• Support upstream and downstream process optimisation.
• Apply engineering calculations and computational modelling to technical challenges.
• Use tools such as Python, MATLAB, CFD and Dynochem.
• Prepare technical reports, presentations and project updates.
• Work to GLP and relevant laboratory safety standards.
• Collaborate with laboratory, facilities and equipment teams.
• Mentor and train junior team members where required.

REQUIREMENTS

• MSc with one to two years of relevant industry experience, or bachelor’s degree with at least three years of experience.
• Experience in process-development engineering or MSAT support.
• Strong chemical-engineering fundamentals across upstream or downstream bioprocessing.
• Knowledge of QbD, Design of Experiments and process characterisation.
• Experience with process scale-up, scale-down and technology transfer.
• Experience with JMP, Minitab, R, Python or MATLAB.
• Strong project-management, communication and presentation skills.
• Ability to work effectively in a multidisciplinary environment.

DESIRABLE EXPERIENCE

• Raman, NIR, FTIR, UV-Vis or other PAT technologies.
• Chemometric model development and implementation.
• Mechanistic modelling using gPROMS, Aspen Plus, SIMCA, MATLAB SimBiology or similar platforms.
• Bioprocess technology transfer from laboratory to manufacturing scale.
• Knowledge of GMP and FDA, EMA or ICH requirements.

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