Clinical Project Manager

Overview

Our client, a venture-backed clinical-stage biotech, is advancing its lead candidate into Phase 1 and needs a Senior Clinical Project Manager to run day-to-day delivery at US sites — initially freelance, with a route to permanent as the pipeline scales.

Key Responsibilities

• Own end-to-end operational delivery of the Phase 1 study across US sites

• Act as primary contact between sponsor, CRO, and clinical sites

• Manage timelines, budget, and risk log

• Lead US site selection, activation, and start-up

• Oversee vendors (central labs, IRT, imaging, etc.)

• Ensure GCP/ICH compliance and inspection readiness

• Chair cross-functional study team meetings

• Track enrollment and resolve site-level issues

• Report progress and risks to leadership

Requirements

• 7+ years clinical project management in biotech

• Direct experience running Phase 1 / first-in-human trials

• CNS, neurology, or immunology experience preferred

• Track record managing US-only site networks

• Strong CRO and vendor oversight experience

• Comfortable in a lean, hands-on biotech environment

Engagement

• Freelance/contract, with a defined path to permanent conversion

• Fully remote, US-based

• Start date and rate: TBC